Ovarian cancer is the second most common gynecologic malignancy . There are approximately 20,000 new cases and 12,800 cancer-related deaths expected from ovarian cancer each year in the US.
Endometrial cancer is the most common gynecologic cancer with over 65,000 new cases and 12,500 deaths in the US in 2022. 90% of the uterine cancers are endometrial with the remaining being sarcomas of the uterine wall.
In the United States, over 12,000 new cases of invasive cervical cancer and approximately 4,000 cervical cancer-related deaths occur each year. Cervical cancer is the third most common cancer diagnosis and cause of death among gynecologic cancers in the United States.
Vulvar cancer is the fourth most common gynecologic cancer and comprises five percent of malignancies of the female genital tract. Within the United States, approximately 4700 cases are diagnosed each year, with nearly 1000 of those women expected to succumb to their disease. Although various histologic subtypes of vulvar cancer exist, the vast majority is comprised of squamous cell carcinoma (SCC).
Vaginal cancer comprises approximately three percent of all malignant neoplasms of the female genital tract. Approximately 2,900 cases are diagnosed annually in the United States, with about 800 deaths.
Gestational Trophoblastic Disease (GTD) is the abnormal growth of cells in the uterus that is usually associated with an abnormal placental or pregnancy tissue. Usually this is diagnosed when a woman suspects or knows she is pregnant. Typically there is bleeding in these pregnancies or an abnormal ultrasound.